Llandudno FC players Dan Jones and Rowan Davies have both suffered ruptured ACLs.
They will be out of action for the next 14 months.
Manager Jordan Hadaway said: "It’s hard to take as both lads are absolutely brilliant and add so much to the group.
"They will be a massive miss for us on the pitch.
"However I know them both and they will return stronger and we will support them to ensure they are back stronger."
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